GHK-Cu
Copper Tripeptide-1 / Glycyl-L-histidyl-L-lysine
A naturally occurring copper peptide tripeptide-complex. Supplied as a lyophilized research compound in 50mg and 100mg formats.
Frequently Researched Together
Longevity, Recovery & Skin Research Compound
Compound Information
Technical specifications
What Is GHK-Cu?
Stability Information
-20C·up to 2 years
2-8C·up to 30 days
Frequently Asked Questions
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine, first isolated from human plasma in 1973. It is supplied as a lyophilized research compound.
Published work covers wound-healing models in animals, collagen and glycosaminoglycan synthesis in cultured fibroblasts, and gene-expression studies. Most data are preclinical.
Store lyophilized vials at -20°C, dry and protected from light, and reconstitute with a suitable diluent such as bacteriostatic water according to your lab's protocol. Halo does not provide dosing or administration guidance.
No. GHK-Cu is sold strictly for laboratory research use and is not intended for human or veterinary use.
GHK is the bare tripeptide. GHK-Cu is GHK bound to a copper(II) ion, which gives the compound its blue color.
Yes. GHK has been measured in human plasma, saliva and urine, and reported plasma levels decline with age.
Sources & References
Peer-reviewed research
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
2018 PMID: 29986520 Pickart L, Margolina A View SourceGHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
2015 PMID: 26236730 Pickart L, Vasquez-Soltero JM,... View SourceThe effect of topical tripeptide-copper complex on healing of ischemic open wounds
2003 Canapp SO Jr, Farese JP, Schultz GS, et al.Stimulation of collagen production by copper-peptide complex
2007 Appa Y et al.Biotinylated GHK peptide incorporated collagenous matrix: a novel biomaterial for dermal wound healing in rats
2005 Arul V, Gopinath D, Gomathi K, Jayakumar REffects of Topical Copper Tripeptide Complex on CO2 Laser-Resurfaced Skin
2006 DOI: 10.1001/archfaci.8.4.252 Miller TR et al.Role of topical peptides in preventing or treating aged skin
2009 Gorouhi F, Maibach HIThe human tri-peptide GHK and tissue remodeling
2008 Pickart LAnti-inflammatory effects of GHK-Cu
2012Not for human consumption. This product is sold exclusively for research and educational purposes.